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Total flavones of Abelmoschus manihot improve diabetic nephropathy by inhibiting the iRhom2/TACE signalling pathway activity in rats

Context: Total flavones extracted from Abelmoschus manihot L. (Malvaceae) medic (TFA) have been proven clinically effective at improving renal inflammation and glomerular injury in chronic kidney disease (CKD). Objective: This study evaluated the function of TFA as an inhibitor of iRhom2/TACE (tumou...

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Detalhes bibliográficos
Publicado no:Pharm Biol
Main Authors: Liu, Su, Ye, Lifang, Tao, Jing, Ge, Chao, Huang, Liji, Yu, Jiangyi
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6130561/
https://ncbi.nlm.nih.gov/pubmed/29221422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/13880209.2017.1412467
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