Functional and structural connectome properties in the 5XFAD transgenic mouse model of Alzheimer’s disease

Neurodegeneration in Alzheimer’s disease (AD) is associated with amyloid-beta peptide accumulation into insoluble amyloid plaques. The five-familial AD (5XFAD) transgenic mouse model exhibits accelerated amyloid-beta deposition, neuronal dysfunction, and cognitive impairment. We aimed to determine w...

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Publicat a:Netw Neurosci
Autors principals: Kesler, Shelli R., Acton, Paul, Rao, Vikram, Ray, William J.
Format: Artigo
Idioma:Inglês
Publicat: MIT Press 2018
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6130552/
https://ncbi.nlm.nih.gov/pubmed/30215035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1162/netn_a_00048
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