Lipopolysaccharide from Rhodobacter sphaeroides (TLR4 antagonist) attenuates hypersensitivity and modulates nociceptive factors

Context: Accumulating evidence has demonstrated that Toll-like receptors (TLRs), especially TLR4 localized on microglia/macrophages, may play a significant role in nociception. Objective: We examine the role of TLR4 in a neuropathic pain model. Using behavioural/biochemical methods, we examined the...

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Publicat a:Pharm Biol
Autors principals: Jurga, Agnieszka M., Rojewska, Ewelina, Makuch, Wioletta, Mika, Joanna
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2018
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6130482/
https://ncbi.nlm.nih.gov/pubmed/29656686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/13880209.2018.1457061
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