The impact of cryosolution thermal contraction on proteins and protein crystals: volumes, conformation and order

Cryocooling of macromolecular crystals is commonly employed to limit radiation damage during X-ray diffraction data collection. However, cooling itself affects macromolecular conformation and often damages crystals via poorly understood processes. Here, the effects of cryosolution thermal contractio...

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Detalhes bibliográficos
Publicado no:Acta Crystallogr D Struct Biol
Main Authors: Juers, Douglas H., Farley, Christopher A., Saxby, Christopher P., Cotter, Rosemary A., Cahn, Jackson K. B., Holton-Burke, R. Conor, Harrison, Kaitlin, Wu, Zhenguo
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2018
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6130464/
https://ncbi.nlm.nih.gov/pubmed/30198901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2059798318008793
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