Structural basis for antibiotic resistance mediated by the Bacillus subtilis ABCF ATPase VmlR

Many Gram-positive pathogenic bacteria employ ribosomal protection proteins (RPPs) to confer resistance to clinically important antibiotics. In Bacillus subtilis, the RPP VmlR confers resistance to lincomycin (Lnc) and the streptogramin A (S(A)) antibiotic virginiamycin M (VgM). VmlR is an ATP-bindi...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Crowe-McAuliffe, Caillan, Graf, Michael, Huter, Paul, Takada, Hiraku, Abdelshahid, Maha, Nováček, Jiří, Murina, Victoriia, Atkinson, Gemma C., Hauryliuk, Vasili, Wilson, Daniel N.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6130385/
https://ncbi.nlm.nih.gov/pubmed/30126986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1808535115
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