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Phospholipid retention in the absence of asymmetry strengthens the outer membrane permeability barrier to last-resort antibiotics

The outer membrane of Gram-negative bacteria is a critical barrier that prevents entry of noxious compounds. Integral to this functionality is the presence of lipopolysaccharide (LPS) or lipooligosaccharide (LOS), a molecule that is located exclusively in the outer leaflet of the outer membrane. Its...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Powers, Matthew J., Trent, M. Stephen
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6130378/
https://ncbi.nlm.nih.gov/pubmed/30087182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1806714115
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