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Phospholipid retention in the absence of asymmetry strengthens the outer membrane permeability barrier to last-resort antibiotics
The outer membrane of Gram-negative bacteria is a critical barrier that prevents entry of noxious compounds. Integral to this functionality is the presence of lipopolysaccharide (LPS) or lipooligosaccharide (LOS), a molecule that is located exclusively in the outer leaflet of the outer membrane. Its...
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Publicado no: | Proc Natl Acad Sci U S A |
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Main Authors: | , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2018
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6130378/ https://ncbi.nlm.nih.gov/pubmed/30087182 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1806714115 |
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