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On the importance of accounting for nuclear quantum effects in ab initio calibrated force fields in biological simulations

In many important processes in chemistry, physics, and biology the nuclear degrees of freedom cannot be described using the laws of classical mechanics. At the same time, the vast majority of molecular simulations that employ wide-coverage force fields treat atomic motion classically. In light of th...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Pereyaslavets, Leonid, Kurnikov, Igor, Kamath, Ganesh, Butin, Oleg, Illarionov, Alexey, Leontyev, Igor, Olevanov, Michael, Levitt, Michael, Kornberg, Roger D., Fain, Boris
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6130346/
https://ncbi.nlm.nih.gov/pubmed/30127031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1806064115
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