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Total Synthesis of the Norhasubanan Alkaloid Stephadiamine

Stephadiamine is an unusual alkaloid isolated from the vine Stephania japonica. It features a norhasubanan skeleton, and contains two adjacent α-tertiary amines, which renders it an attractive synthetic target. Here, we present the first total synthesis of stephadiamine, which hinges on an efficient...

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Publicado en:J Am Chem Soc
Autores principales: Hartrampf, Nina, Winter, Nils, Pupo, Gabriele, Stoltz, Brian M., Trauner, Dirk
Formato: Artigo
Lenguaje:Inglês
Publicado: 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6130314/
https://ncbi.nlm.nih.gov/pubmed/29889502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.8b01918
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