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Inhibition of Glycolysis Reduces Disease Severity in an Autoimmune Model of Rheumatoid Arthritis
The K/BxN mouse is a spontaneous model of arthritis driven by T cell receptor transgenic CD4(+) T cells from the KRN strain that are activated by glucose-6-phosphate isomerase (GPI) peptides presented by the H-2(g7) allele from the NOD strain. It is a model of autoimmune seropositive arthritis becau...
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| Publicado no: | Front Immunol |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6130222/ https://ncbi.nlm.nih.gov/pubmed/30233578 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.01973 |
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