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1,25(OH)(2)D(3) suppresses proinflammatory responses by inhibiting Th1 cell differentiation and cytokine production through the JAK/STAT pathway

1,25(OH)(2)D(3) is an immune modulation hormone with beneficial effects on T cell- mediated autoimmune diseases. The purpose of the present study is to investigate the direct effects of vitamin D on Bacillus Calmette Guerin (BCG)-infected CD4+ T cells in both VDR-deficient (VDR-/-) mice and wild typ...

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Detalhes bibliográficos
Publicado no:Am J Transl Res
Main Authors: Zhang, Zehua, Chen, Feifan, Li, Jianhua, Luo, Fei, Hou, Tianyong, Xu, Jianzhong, Sun, Dong
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6129541/
https://ncbi.nlm.nih.gov/pubmed/30210711
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