Context matters: Th2 polarization resulting from pollen composition and not from protein-intrinsic allergenicity

BACKGROUND: Over 100 million people worldwide suffer from birch pollen allergy. However, identification of molecular determinants driving Th2-biased allergic sensitization to Bet v 1, the major birch pollen allergen, remains elusive. OBJECTIVE: Here, we examined whether Bet v 1 or the pollen matrix...

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Pubblicato in:J Allergy Clin Immunol
Autori principali: Aglas, Lorenz, Gilles, Stefanie, Bauer, Renate, Huber, Sara, Araujo, Galber R., Mueller, Geoffrey, Scheiblhofer, Sandra, Amisi, Marie, Dang, Hieu-Hoa, Briza, Peter, Bohle, Barbara, Horejs-Hoeck, Jutta, Traidl-Hoffmann, Claudia, Ferreira, Fatima
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6129402/
https://ncbi.nlm.nih.gov/pubmed/29782896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2018.05.004
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