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iCFN: an efficient exact algorithm for multistate protein design

MOTIVATION: Multistate protein design addresses real-world challenges, such as multi-specificity design and backbone flexibility, by considering both positive and negative protein states with an ensemble of substates for each. It also presents an enormous challenge to exact algorithms that guarantee...

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Bibliographic Details
Published in:Bioinformatics
Main Authors: Karimi, Mostafa, Shen, Yang
Format: Artigo
Language:Inglês
Published: Oxford University Press 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6129278/
https://ncbi.nlm.nih.gov/pubmed/30423073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bty564
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