IL-16/miR-125a axis controls neutrophil recruitment in pristane-induced lung inflammation

Severe lung inflammation and alveolar hemorrhage can be life-threatening in systemic lupus erythematosus (SLE) patients if not treated early and aggressively. Neutrophil influx is the driver key of this pathology, but little is known regarding the molecular events regulating this recruitment. Here,...

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Publicado en:JCI Insight
Main Authors: Smith, Siobhan, Wu, Pei Wen, Seo, Jane J., Fernando, Thilini, Jin, Mengyao, Contreras, Jorge, Montano, Erica N., Gabhann, Joan Ní, Cunningham, Kyle, Widaa, Amro, McCarthy, Eoghan M., Molloy, Eamonn S., Kearns, Grainne, Murphy, Conor C., Kong, Weiping, Björkbacka, Harry, Kornfeld, Hardy, Forbess, Lindsy, Venuturupalli, Swamy, Ishimori, Mariko, Wallace, Daniel, Weisman, Michael H., Jefferies, Caroline A.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 2018
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6129123/
https://ncbi.nlm.nih.gov/pubmed/30089723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.120798
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