Highly efficient genome editing by CRISPR-Cpf1 using CRISPR RNA with a uridinylate-rich 3′-overhang

Genome editing has been harnessed through the development of CRISPR system, and the CRISPR from Prevotella and Francisella 1 (Cpf1) system has emerged as a promising alternative to CRISPR-Cas9 for use in various circumstances. Despite the inherent multiple advantages of Cpf1 over Cas9, the adoption...

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Vydáno v:Nat Commun
Hlavní autoři: Bin Moon, Su, Lee, Jeong Mi, Kang, Jeong Gu, Lee, Nan-Ee, Ha, Dae-In, Kim, Do Yon, Kim, Sun Hee, Yoo, Kwangsun, Kim, Daesik, Ko, Jeong-Heon, Kim, Yong-Sam
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6128929/
https://ncbi.nlm.nih.gov/pubmed/30194297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06129-w
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