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Facultative dosage compensation of developmental genes on autosomes in Drosophila and mouse embryonic stem cells
Haploinsufficiency and aneuploidy are two phenomena, where gene dosage alterations cause severe defects ultimately resulting in developmental failures and disease. One remarkable exception is the X chromosome, where copy number differences between sexes are buffered by dosage compensation systems. I...
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| Veröffentlicht in: | Nat Commun |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group UK
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6128902/ https://ncbi.nlm.nih.gov/pubmed/30194291 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-05642-2 |
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