Pharmacokinetics and toxicology of the neuroprotective e,e,e-methanofullerene(63)-carboxylic acid in mice and primates

BACKGROUND AND OBJECTIVES: Fullerene-based compounds are a novel class of molecules being developed for a variety of biomedical applications, with nearly 1000 publications in this area in the last 4 years alone. One such compound, the e,e,e malonic acid C(60) (C(3)), is a potent catalytic superoxide...

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Udgivet i:Eur J Drug Metab Pharmacokinet
Main Authors: Hardt, Joshua I., Perlmutter, Joel S., Smith, Christopher J., Quick, Kevin L., Wei, Ling, Chakraborty, Subhasish K., Dugan, Laura L.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6128740/
https://ncbi.nlm.nih.gov/pubmed/29520718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13318-018-0464-z
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