Role of S1P/S1PR3 axis in release of CCL20 from human bronchial epithelial cells

BACKGROUND: Sphingosine kinase phosphorylates sphingosine to generate sphingosine 1 phosphate (S1P) following stimulation of the five plasma membrane G-protein-coupled receptors. The objective of this study is to clarify the role of S1P and its receptors (S1PRs), especially S1PR3 in airway epithelia...

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Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: Kawa, Yoshitaka, Nagano, Tatsuya, Yoshizaki, Asuka, Dokuni, Ryota, Katsurada, Masahiro, Terashita, Tomomi, Yasuda, Yuichiro, Umezawa, Kanoko, Yamamoto, Masatsugu, Kamiryo, Hiroshi, Kobayashi, Kazuyuki, Nishimura, Yoshihiro
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2018
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6128515/
https://ncbi.nlm.nih.gov/pubmed/30192865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0203211
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