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Computing threshold antibody levels of protection in vaccine clinical trials: An assessment of methodological bias

In the development of new vaccines, understanding the level of vaccine-induced antibody that is sufficient to protect against disease can simplify and expedite the development and licensing process. If there is an accepted threshold antibody level that is indicative of protection, then smaller trial...

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Publicat a:PLoS One
Autors principals: Voysey, Merryn, Sadarangani, Manish, Pollard, Andrew J., Fanshawe, Thomas R.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2018
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6128451/
https://ncbi.nlm.nih.gov/pubmed/30192787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0202517
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