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Computing threshold antibody levels of protection in vaccine clinical trials: An assessment of methodological bias

In the development of new vaccines, understanding the level of vaccine-induced antibody that is sufficient to protect against disease can simplify and expedite the development and licensing process. If there is an accepted threshold antibody level that is indicative of protection, then smaller trial...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Voysey, Merryn, Sadarangani, Manish, Pollard, Andrew J., Fanshawe, Thomas R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6128451/
https://ncbi.nlm.nih.gov/pubmed/30192787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0202517
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