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Accelerating glioblastoma drug discovery: Convergence of patient-derived models, genome editing and phenotypic screening

Patients diagnosed with glioblastoma (GBM) continue to face a bleak prognosis. It is critical that new effective therapeutic strategies are developed. GBM stem cells have molecular hallmarks of neural stem and progenitor cells and it is possible to propagate both non-transformed normal neural stem c...

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Bibliografiska uppgifter
I publikationen:Mol Cell Neurosci
Huvudupphovsmän: O'Duibhir, Eoghan, Carragher, Neil O., Pollard, Steven M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6128397/
https://ncbi.nlm.nih.gov/pubmed/27825983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mcn.2016.11.001
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