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Accelerating glioblastoma drug discovery: Convergence of patient-derived models, genome editing and phenotypic screening

Patients diagnosed with glioblastoma (GBM) continue to face a bleak prognosis. It is critical that new effective therapeutic strategies are developed. GBM stem cells have molecular hallmarks of neural stem and progenitor cells and it is possible to propagate both non-transformed normal neural stem c...

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Bibliografske podrobnosti
izdano v:Mol Cell Neurosci
Main Authors: O'Duibhir, Eoghan, Carragher, Neil O., Pollard, Steven M.
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6128397/
https://ncbi.nlm.nih.gov/pubmed/27825983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mcn.2016.11.001
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