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Discovery of the Novel Entecavir‐Resistant Hepatitis B Virus Reverse Transcriptase A181C Substitution From an Integrated Genotypic Analysis

Entecavir (ETV) is a first‐line therapy for chronic hepatitis B virus (HBV), demonstrating potent suppression of HBV DNA and a high barrier to viral resistance. Previous studies revealed that ETV‐resistant (ETVr) HBV DNA resulted from substitutions in the HBV reverse transcriptase (RT) at positions...

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Bibliografski detalji
Izdano u:Hepatol Commun
Glavni autori: Rose, Ronald E., Hernandez, Dennis, Falk, Paul J., Ericson, Karen, Zhou, Nannan, Thiry, Alexandra, McPhee, Fiona
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6128232/
https://ncbi.nlm.nih.gov/pubmed/30202825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep4.1231
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