Artesunate-induced mitophagy alters cellular redox status

Artesunate (ART) is a prominent anti-malarial with significant anti-cancer properties. Our previous studies showed that ART enhances lysosomal function and ferritin degradation, which was necessary for its anti-cancer properties. ART targeting to mitochondria also significantly improved its efficacy...

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Bibliographische Detailangaben
Veröffentlicht in:Redox Biol
Hauptverfasser: Zhang, Jianbin, Sun, Xin, Wang, Liming, Wong, Yin Kwan, Lee, Yew Mun, Zhou, Chao, Wu, Guoqing, Zhao, Tongwei, Yang, Liu, Lu, Liqin, Zhong, Jianing, Huang, Dongsheng, Wang, Jigang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2018
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6128040/
https://ncbi.nlm.nih.gov/pubmed/30196190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2018.07.025
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