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The roles of aromatic residues in the glycine receptor transmembrane domain

BACKGROUND: Cys-loop receptors play important roles in fast neuronal signal transmission. Functional receptors are pentamers, with each subunit having an extracellular, transmembrane (TM) and intracellular domain. Each TM domain contains 4 α-helices (M1–M4) joined by loops of varying lengths. Many o...

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Detalhes bibliográficos
Publicado no:BMC Neurosci
Main Authors: Tang, Bijun, Lummis, Sarah C. R.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6127993/
https://ncbi.nlm.nih.gov/pubmed/30189850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12868-018-0454-8
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