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Ethanol Modulation is Quantitatively Determined by the Transmembrane Domain of Human α1 Glycine Receptors

BACKGROUND: Mutagenesis and labeling studies have identified amino acids from the human α1 glycine receptor (GlyR) extracellular, transmembrane (TM), and intracellular domains in mediating ethanol potentiation. However, limited high-resolution structural data for physiologically relevant receptors i...

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Publicado en:Alcohol Clin Exp Res
Autores principales: Horani, Suzzane, Stater, Evan P., Corringer, Pierre-Jean, Trudell, James R., Harris, R. Adron, Howard, Rebecca J.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4452391/
https://ncbi.nlm.nih.gov/pubmed/25973519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acer.12735
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