Inhibition of STAT3 in gastric cancer: role of pantoprazole as SHP-1 inducer

BACKGROUND: We investigated the inhibitory effect of pantoprazole on signal transducer and activator of transcription 3 (STAT3) activity and invasiveness of gastric adenocarcinoma cells, and the role of SH2-containing protein tyrosine phosphatase 1 (SHP-1) in mediating role. METHODS: We used AGS and...

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Bibliografiske detaljer
Udgivet i:Cell Biosci
Main Authors: Koh, Jin Sung, Joo, Moon Kyung, Park, Jong-Jae, Yoo, Hyo Soon, Choi, Byung Il, Lee, Beom Jae, Chun, Hoon Jai, Lee, Sang Woo
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2018
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6127946/
https://ncbi.nlm.nih.gov/pubmed/30202514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13578-018-0248-9
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