Decreased methylation in the SNAI2 and ADAM23 genes associated with de-differentiation and haematogenous dissemination in breast cancers

BACKGROUND: In breast cancer (BC), deregulation of DNA methylation leads to aberrant expressions and functions of key regulatory genes. In our study, we investigated the relationship between the methylation profiles of genes associated with cancer invasivity and clinico-pathological parameters. In d...

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Veröffentlicht in:BMC Cancer
Hauptverfasser: Kalinkova, Lenka, Zmetakova, Iveta, Smolkova, Bozena, Minarik, Gabriel, Sedlackova, Tatiana, Horvathova Kajabova, Viera, Cierna, Zuzana, Mego, Michal, Fridrichova, Ivana
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2018
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6127923/
https://ncbi.nlm.nih.gov/pubmed/30189837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-018-4783-x
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