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Decreased methylation in the SNAI2 and ADAM23 genes associated with de-differentiation and haematogenous dissemination in breast cancers

BACKGROUND: In breast cancer (BC), deregulation of DNA methylation leads to aberrant expressions and functions of key regulatory genes. In our study, we investigated the relationship between the methylation profiles of genes associated with cancer invasivity and clinico-pathological parameters. In d...

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Vydáno v:BMC Cancer
Hlavní autoři: Kalinkova, Lenka, Zmetakova, Iveta, Smolkova, Bozena, Minarik, Gabriel, Sedlackova, Tatiana, Horvathova Kajabova, Viera, Cierna, Zuzana, Mego, Michal, Fridrichova, Ivana
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6127923/
https://ncbi.nlm.nih.gov/pubmed/30189837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-018-4783-x
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