Topical Lyophilized Targeted Lipid Nanoparticles in the Restoration of Skin Barrier Function following Burn Wound

Lyophilized keratinocyte-targeted nanocarriers (TLN(κ)) loaded with locked nucleic acid (LNA) modified anti-miR were developed for topical application to full thickness burn injury. TLN(κ) were designed to selectively deliver LNA-anti-miR-107 to keratinocytes using the peptide sequence ASKAIQVFLLAG....

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Detalhes bibliográficos
Publicado no:Mol Ther
Main Authors: Li, Jilong, Ghatak, Subhadip, El Masry, Mohamed S., Das, Amitava, Liu, Yang, Roy, Sashwati, Lee, Robert J., Sen, Chandan K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2018
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6127501/
https://ncbi.nlm.nih.gov/pubmed/29802017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2018.04.021
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