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Topical Lyophilized Targeted Lipid Nanoparticles in the Restoration of Skin Barrier Function following Burn Wound
Lyophilized keratinocyte-targeted nanocarriers (TLN(κ)) loaded with locked nucleic acid (LNA) modified anti-miR were developed for topical application to full thickness burn injury. TLN(κ) were designed to selectively deliver LNA-anti-miR-107 to keratinocytes using the peptide sequence ASKAIQVFLLAG....
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| Publié dans: | Mol Ther |
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| Auteurs principaux: | , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society of Gene & Cell Therapy
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6127501/ https://ncbi.nlm.nih.gov/pubmed/29802017 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2018.04.021 |
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