Local DNA Sequence Controls Asymmetry of DNA Unwrapping from Nucleosome Core Particles

DNA is tightly wrapped around histone proteins in nucleosome core particles (NCPs) yet must become accessible for processing in the cell. This accessibility, a key component of transcription regulation, is influenced by the properties of both the histone proteins and the DNA itself. Small angle x-ra...

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Bibliographic Details
Published in:Biophys J
Main Authors: Mauney, Alexander W., Tokuda, Joshua M., Gloss, Lisa M., Gonzalez, Oscar, Pollack, Lois
Format: Artigo
Language:Inglês
Published: The Biophysical Society 2018
Subjects:
Nucleic Acids and Genome Biophysics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6127449/
https://ncbi.nlm.nih.gov/pubmed/30072033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2018.07.009
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