Design and characterisation of a dissolving microneedle patch for intradermal vaccination with heat-inactivated bacteria: A proof of concept study

This work describes the formulation and evaluation of dissolving microneedle patches (MNs) for intradermal delivery of heat-inactivated bacteria. Pseudomonas aeruginosa, strain PA01, was used as a model bacterium. Utilising a simple, cost effective fabrication process, P. aeruginosa was heat-inactiv...

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Vydáno v:Int J Pharm
Hlavní autoři: Rodgers, Aoife M., McCrudden, Maelíosa T.C., Vincente-Perez, Eva.M., Dubois, Alice V., Ingram, Rebecca J., Larrañeta, Eneko, Kissenpfennig, Adrien, Donnelly, Ryan F.
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier/North-Holland Biomedical Press 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6127419/
https://ncbi.nlm.nih.gov/pubmed/30048778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpharm.2018.07.049
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