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Enhanced Intradermal Delivery of Nanosuspensions of Antifilariasis Drugs Using Dissolving Microneedles: A Proof of Concept Study

Conventional oral administration of antifilariasis drugs results in nonspecific targeting of the drugs and the intradermal delivery of nanoparticles with sizes of <100 nm could be used to improve lymphatic uptake. This study investigated the combination of nanosuspension and dissolving microneedl...

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Bibliographic Details
Published in:Pharmaceutics
Main Authors: Permana, Andi Dian, McCrudden, Maelíosa T. C., Donnelly, Ryan F.
Format: Artigo
Language:Inglês
Published: MDPI 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6680801/
https://ncbi.nlm.nih.gov/pubmed/31319602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics11070346
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