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Not All Immune Checkpoints Are Created Equal

Antibodies that block T cell inhibition via the immune checkpoints CTLA-4 and PD-1 have revolutionized cancer therapy during the last 15 years. T cells express additional inhibitory surface receptors that are considered to have potential as targets in cancer immunotherapy. Antibodies against LAG-3 a...

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Bibliografiske detaljer
Udgivet i:Front Immunol
Main Authors: De Sousa Linhares, Annika, Leitner, Judith, Grabmeier-Pfistershammer, Katharina, Steinberger, Peter
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6127213/
https://ncbi.nlm.nih.gov/pubmed/30233564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.01909
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