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Effect of Lapatinib on Meningioma Growth in Adults with Neurofibromatosis Type 2

INTRODUCTION: Epidermal growth factor receptors EGFR and ErbB2 are overexpressed in schwannomas and meningiomas. Preclinical and clinical data indicate that lapatinib, an EGFR/ErbB2 inhibitor, has antitumor activity against vestibular schwannomas in neurofibromatosis type 2 (NF2) patients. Its antit...

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Dades bibliogràfiques
Publicat a:J Neurooncol
Autors principals: Osorio, Diana S., Hu, Jessica, Mitchell, Carole, Allen, Jeffrey C., Stanek, Joseph, Hagiwara, Mari, Karajannis, Matthias A.
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6126973/
https://ncbi.nlm.nih.gov/pubmed/29948766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11060-018-2922-5
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