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Effect of Lapatinib on Meningioma Growth in Adults with Neurofibromatosis Type 2
INTRODUCTION: Epidermal growth factor receptors EGFR and ErbB2 are overexpressed in schwannomas and meningiomas. Preclinical and clinical data indicate that lapatinib, an EGFR/ErbB2 inhibitor, has antitumor activity against vestibular schwannomas in neurofibromatosis type 2 (NF2) patients. Its antit...
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| 出版年: | J Neurooncol |
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| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6126973/ https://ncbi.nlm.nih.gov/pubmed/29948766 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11060-018-2922-5 |
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