Differential 5-Year Brain Atrophy Rates in Cognitively Declining and Stable APOE-ε4 Elders

OBJECTIVE: The Apolipoprotein E (APOE) ε4 allele is the most important genetic risk factor for late onset Alzheimer’s disease (LOAD). Many ε4 carriers, however, never develop Alzheimer’s disease. The purpose of this study is to characterize the variability in phenotypic expression of the ε4 allele,...

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Gepubliceerd in:Neuropsychology
Hoofdauteurs: Kelly, Dana A., Seidenberg, Michael, Reiter, Katherine, Nielson, Kristy A., Woodard, John L., Smith, J. Carson, Durgerian, Sally, Rao, Stephen M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2018
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6126943/
https://ncbi.nlm.nih.gov/pubmed/29911873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1037/neu0000444
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