Five-year longitudinal brain volume change in healthy elders at genetic risk for Alzheimer’s disease

Neuropathological changes associated with Alzheimer’s disease (AD) precede symptom onset by more than a decade. Possession of an Apolipoprotein-E (APOE) ε4 allele is the strongest genetic risk factor for late onset AD. Cross-sectional studies of cognitively intact elders have noted smaller hippocamp...

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Detalhes bibliográficos
Publicado no:J Alzheimers Dis
Main Authors: Reiter, Katherine, Nielson, Kristy A., Durgerian, Sally, Woodard, John L., Smith, J. Carson, Seidenberg, Michael, Kelly, Dana A., Rao, Stephen M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5924681/
https://ncbi.nlm.nih.gov/pubmed/27834774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-160504
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