Differential 5-Year Brain Atrophy Rates in Cognitively Declining and Stable APOE-ε4 Elders

OBJECTIVE: The Apolipoprotein E (APOE) ε4 allele is the most important genetic risk factor for late onset Alzheimer’s disease (LOAD). Many ε4 carriers, however, never develop Alzheimer’s disease. The purpose of this study is to characterize the variability in phenotypic expression of the ε4 allele,...

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Publicat a:Neuropsychology
Autors principals: Kelly, Dana A., Seidenberg, Michael, Reiter, Katherine, Nielson, Kristy A., Woodard, John L., Smith, J. Carson, Durgerian, Sally, Rao, Stephen M.
Format: Artigo
Idioma:Inglês
Publicat: 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6126943/
https://ncbi.nlm.nih.gov/pubmed/29911873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1037/neu0000444
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