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Xenotransplanted Pig Sertoli Cells Inhibit Both the Alternative and Classical Pathways of Complement-Mediated Cell Lysis While Pig Islets Are Killed

Xenotransplantation has vast clinical potential but is limited by the potent immune responses generated against xenogeneic tissue. Immune-privileged Sertoli cells (SCs) survive xenotransplantation long term (>90 days) without immunosuppression, making SCs an ideal model to identify xenograft surv...

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Dettagli Bibliografici
Pubblicato in:Cell Transplant
Autori principali: Wright, Kandis, Dziuk, Rachel, Mital, Payal, Kaur, Gurvinder, Dufour, Jannette M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6126928/
https://ncbi.nlm.nih.gov/pubmed/27305664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3727/096368916X692032
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