Interferon-stimulated TRIM69 interrupts dengue virus replication by ubiquitinating viral nonstructural protein 3

In order to eliminate viral infections, hundreds of interferon-stimulated genes (ISGs) are induced via type I interferons (IFNs). However, the functions and mechanisms of most ISGs are largely unclear. A tripartite motif (TRIM) protein encoding gene TRIM69 is induced by dengue virus (DENV) infection...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Wang, Kezhen, Zou, Chunling, Wang, Xiujuan, Huang, Chenxiao, Feng, Tingting, Pan, Wen, Wu, Qihan, Wang, Penghua, Dai, Jianfeng
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6126873/
https://ncbi.nlm.nih.gov/pubmed/30142214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007287
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