Proteomic analysis of monolayer-integrated proteins on lipid droplets identifies amphipathic interfacial α-helical membrane anchors

Despite not spanning phospholipid bilayers, monotopic integral proteins (MIPs) play critical roles in organizing biochemical reactions on membrane surfaces. Defining the structural basis by which these proteins are anchored to membranes has been hampered by the paucity of unambiguously identified MI...

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Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Pataki, Camille I., Rodrigues, João, Zhang, Lichao, Qian, Junyang, Efron, Bradley, Hastie, Trevor, Elias, Joshua E., Levitt, Michael, Kopito, Ron R.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2018
Fag:
PNAS Plus
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6126764/
https://ncbi.nlm.nih.gov/pubmed/30104359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1807981115
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