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Expression of long non-coding RNA YIYA promotes glycolysis in breast cancer

Long non-coding RNA (lncRNA) have yet to be linked to cancer metabolism. Here we report that upregulation of the lncRNA LINC00538 (YIYA) promotes glycolysis, cell proliferation and tumor growth in in breast cancer. YIYA associated with the cytosolic cyclin-dependent kinase CDK6 and regulated CDK6-de...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Xing, Zhen, Zhang, Yanyan, Liang, Ke, Yan, Liang, Xiang, Yu, Li, Chunlai, Hu, Qingsong, Jin, Feng, Putluri, Vasanta, Putluri, Nagireddy, Coarfa, Cristian, Sreekumar, Arun, Park, Peter K., Nguyen, Tina K., Wang, Shouyu, Zhou, Jianwei, Zhou, Yan, Marks, Jeffrey R., Hawke, David H., Hung, Mien-Chie, Yang, Liuqing, Han, Leng, Ying, Haoqiang, Lin, Chunru
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6126676/
https://ncbi.nlm.nih.gov/pubmed/29967256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-17-0385
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