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Regioselective O-Glycosylation of Nucleosides via the Temporary 2',3'-Diol Protection by a Boronic Ester for the Synthesis of Disaccharide Nucleosides

Disaccharide nucleosides, which consist of disaccharide and nucleobase moieties, have been known as a valuable group of natural products having multifarious bioactivities. Although chemical O-glycosylation is a commonly beneficial strategy to synthesize disaccharide nucleosides, the preparation of s...

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Vydáno v:J Vis Exp
Hlavní autoři: Someya, Hidehisa, Itoh, Taiki, Kato, Mebae, Aoki, Shin
Médium: Artigo
Jazyk:Inglês
Vydáno: MyJove Corporation 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6126549/
https://ncbi.nlm.nih.gov/pubmed/30102273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/57897
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