Eukaryotic translation initiation factor 3 subunit G (EIF3G) resensitized HCT116/5-Fu to 5-fluorouracil (5-Fu) via inhibition of MRP and MDR1

PURPOSE: Colorectal cancer (CRC) has become a predominant cancer and accounts for approximately 10% of cancer-related mortality. Drug resistance still remains a priority mortality factor for patients due to no available therapeutic alternatives. The purpose of the present study was to investigate th...

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Enregistré dans:
Détails bibliographiques
Publié dans:Onco Targets Ther
Auteurs principaux: Yang, Chenggang, Liu, Xin, Li, Chaobin, Li, Shuangjing, Du, Wenfeng, Yang, Daogui
Format: Artigo
Langue:Inglês
Publié: Dove Medical Press 2018
Sujets:
Original Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6126502/
https://ncbi.nlm.nih.gov/pubmed/30214237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S170854
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