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Suppression of microRNA-31 increases sensitivity to 5-FU at an early stage, and affects cell migration and invasion in HCT-116 colon cancer cells

BACKGROUND: MicroRNAs (miRNAs) are endogenously expressed noncoding RNAs with important biological and pathological functions. Although several studies have shown that microRNA-31 (miR-31) is obviously up-regulated in colorectal cancer (CRC), there is no study on the functional roles of miR-31 in CR...

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Autors principals: Wang, Chao-Jie, Stratmann, Johannes, Zhou, Zong-Guang, Sun, Xiao-Feng
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2994822/
https://ncbi.nlm.nih.gov/pubmed/21062447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-10-616
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