Biochemical Characterization of Isoniazid-resistant Mycobacterium tuberculosis: Can the Analysis of Clonal Strains Reveal Novel Targetable Pathways?

Tuberculosis (TB) continues to be an important public health threat worldwide, due in part to drug resistant Mycobacterium tuberculosis (Mtb) strains. The United States recently reported a shortage of isoniazid (INH), which could drive higher INH resistance rates. Changes in the Mtb proteome before...

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Detalles Bibliográficos
Publicado en:Mol Cell Proteomics
Autores principales: Nieto R, Luisa Maria, Mehaffy, Carolina, Islam, M. Nurul, Fitzgerald, Bryna, Belisle, John, Prenni, Jessica, Dobos, Karen
Formato: Artigo
Lenguaje:Inglês
Publicado: The American Society for Biochemistry and Molecular Biology 2018
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Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6126390/
https://ncbi.nlm.nih.gov/pubmed/29844232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.RA118.000821
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