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Suppression of Harmaline Tremor by Activation of an Extrasynaptic GABA(A) Receptor: Implications for Essential Tremor

BACKGROUND: Metabolic imaging has revealed excessive cerebellar activity in essential tremor patients. Golgi cells control cerebellar activity by releasing gamma-aminobutyric acid (GABA) onto synaptic and extrasynaptic receptors on cerebellar granule cells. We postulated that the extrasynaptic GABA(...

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Detalhes bibliográficos
Publicado no:Tremor Other Hyperkinet Mov (N Y)
Main Authors: Handforth, Adrian, Kadam, Pournima A., Kosoyan, Hovsep P., Eslami, Pirooz
Formato: Artigo
Idioma:Inglês
Publicado em: Columbia University Libraries/Information Services 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6125735/
https://ncbi.nlm.nih.gov/pubmed/30191083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7916/D8JW9X9K
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