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Performance evaluation of pathogenicity-computation methods for missense variants

With expanding applications of next-generation sequencing in medical genetics, increasing computational methods are being developed to predict the pathogenicity of missense variants. Selecting optimal methods can accelerate the identification of candidate genes. However, the performances of differen...

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Detalles Bibliográficos
Publicado en:Nucleic Acids Res
Main Authors: Li, Jinchen, Zhao, Tingting, Zhang, Yi, Zhang, Kun, Shi, Leisheng, Chen, Yun, Wang, Xingxing, Sun, Zhongsheng
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6125674/
https://ncbi.nlm.nih.gov/pubmed/30060008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky678
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