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CancerDetector: ultrasensitive and non-invasive cancer detection at the resolution of individual reads using cell-free DNA methylation sequencing data

The detection of tumor-derived cell-free DNA in plasma is one of the most promising directions in cancer diagnosis. The major challenge in such an approach is how to identify the tiny amount of tumor DNAs out of total cell-free DNAs in blood. Here we propose an ultrasensitive cancer detection method...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Li, Wenyuan, Li, Qingjiao, Kang, Shuli, Same, Mary, Zhou, Yonggang, Sun, Carol, Liu, Chun-Chi, Matsuoka, Lea, Sher, Linda, Wong, Wing Hung, Alber, Frank, Zhou, Xianghong Jasmine
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6125664/
https://ncbi.nlm.nih.gov/pubmed/29897492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky423
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