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Mining 3D genome structure populations identifies major factors governing the stability of regulatory communities

Three-dimensional (3D) genome structures vary from cell to cell even in an isogenic sample. Unlike protein structures, genome structures are highly plastic, posing a significant challenge for structure-function mapping. Here we report an approach to comprehensively identify 3D chromatin clusters tha...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Dai, Chao, Li, Wenyuan, Tjong, Harianto, Hao, Shengli, Zhou, Yonggang, Li, Qingjiao, Chen, Lin, Zhu, Bing, Alber, Frank, Jasmine Zhou, Xianghong
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4895025/
https://ncbi.nlm.nih.gov/pubmed/27240697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11549
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