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In Vivo Efficacy of Meropenem with a Novel Non-β-Lactam–β-Lactamase Inhibitor, Nacubactam, against Gram-Negative Organisms Exhibiting Various Resistance Mechanisms in a Murine Complicated Urinary Tract Infection Model

Urinary tract infections (UTIs) are a tremendous burden on the health care system due to the vast number of infections resulting in antibiotic therapy and/or hospitalization. Additionally, these infections are frequently caused by multidrug-resistant (MDR) organisms, limiting the availability of eff...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Monogue, Marguerite L., Giovagnoli, Sara, Bissantz, Caterina, Zampaloni, Claudia, Nicolau, David P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6125527/
https://ncbi.nlm.nih.gov/pubmed/30012751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02596-17
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