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Globular Adiponectin Exerts a Pro-Inflammatory Effect via IκB/NF-κB Pathway Activation and Anti-Inflammatory Effect by IRAK-1 Downregulation

Adiponectin, a hormone produced by adipose tissue, is very abundant in plasma, and its anti- and pro-inflammatory effects are reported. However, the mechanisms of these pro- and anti-inflammatory effects are not fully defined. Herein, we evaluated the dual inflammatory response mechanism of adiponec...

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Publicat a:Mol Cells
Autors principals: Lee, Kyoung-Hee, Jeong, Jiyeong, Woo, Jisu, Lee, Chang-Hoon, Yoo, Chul-Gyu
Format: Artigo
Idioma:Inglês
Publicat: Korean Society for Molecular and Cellular Biology 2018
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6125418/
https://ncbi.nlm.nih.gov/pubmed/30078230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14348/molcells.2018.0005
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